Fall 2020
September 2nd | CRISPR 101
Guest Speaker | Megan Hochstrasser, IGI Education Program Manager |
Optional Review Paper |
The Promise and Challenge of Therapeutic Genome Editing |
September 9th | CRISPR-based genome editing in human cells
Paper |
Multiplex Genome Engineering Using CRISPR/Cas Systems |
September 16th | Student presentation: Agricultural applications
Paper |
Engineering Quantitative Trait Variation for Crop Improvement by Genome Editing |
September 23rd | CRISPR diversity
Guest Speaker | Luis Valentin-Alvarado, PhD student in Banfield and Savage labs at UC Berkeley |
September 30th | Student presentation: Treating sickle cell disease
Paper |
Selection-Free Genome Editing of the Sickle Mutation in Human Adult Hematopoietic Stem/Progenitor Cells |
Press Release |
IGI Makes Progress Toward Treating Sickle Cell Disease with CRISPR-Cas9 |
October 7th | CRISPR toolbox: Directed evolution
Guest Speaker |
Connor Tou (undergrad researcher) and Juan Hurtado (PhD student) in Dueber lab at UC Berkeley |
Paper |
CRISPR-Guided DNA Polymerases Enable Diversification of All Nucleotides in a Tunable Window |
Press Release |
CRISPR Diversifies: Cut, Paste, On, Off, and Now– Evolve! |
October 14th | Student presentation: Editing crops for disease resistance
Paper |
Simultaneous CRISPR/Cas9-mediated editing of cassava eIF4E isoforms nCBP-1 and nCBP-2 reduces cassava brown streak disease symptom severity and incidence |
October 21st | Delivery in plants
Guest Speaker |
Gozde Demirer, former PhD student in Landry lab at UC Berkeley |
Paper |
High Aspect Ratio Nanomaterials Enable Delivery of Functional Genetic Material Without DNA Integration in Mature Plants |
Press Release |
DNA Takes a Ride on a Nanotube: Next Stop, Genome-Edited Crops |
October 28th | Student presentation: Identifying new Cas effectors
Paper | CRISPR-CasΦ from huge phages is a hypercompact genome editor Science | Pausch & Al-Shayeb et al. | July 2020 |
November 4th | Student presentation: CRISPR diagnostics
Review Paper | Nucleic Acid Detection Using CRISPR/Cas Biosensing Technologies ACS Synthetic Biology | Aman et al. | March 2020 |
November 11th | Veterans Day (no meeting)
November 18th | Ethics & regulation
Guest Speaker |
Michael Gomez, postdoc in Staskawicz lab at UC Berkeley |
November 25th | Thanksgiving (no meeting)
December 2nd | Career panel (final meeting of the semester!)