What is CRISPR? How does it work?
The CRISPR-Cas system, sometimes referred to as “CRISPR” for short, is a technology for editing DNA. It is made of a guide RNA and a Cas protein. The guide RNA leads the Cas protein to a particular DNA sequence. The most common and best-studied Cas protein is Cas9. Cas9 acts as molecular scissors, cutting the DNA at the location specified by the guide RNA. When DNA is cut, cells initiate a repair process that can change or edit the DNA sequence. CRISPR can remove, add, or change DNA "letters."