Victoria Gray has sickle cell disease (SCD). SCD is a genetic disease that causes red blood cells to be half moon-shaped instead of round. The sickle-shaped cells block blood vessels, slowing or stopping blood flow. This causes sudden, severe pain. Complications include organ damage, strokes, anemia, and early death.
Victoria is participating in a clinical trial for SCD. She was treated in Nashville, Tennessee, making her the first person in the United States to undergo treatment for a genetic disease using a CRISPR-based therapy.
“They go from cells that make sickle cells to super cells—the cells that help me be better.”
NPR Correspondent Rob Stein broke the story in July 2019. You can follow him to get updates. In early November, he talked with Short Wave host Maddie Sofia and Victoria herself to find out how things are going. Later in November, he talked to Victoria about evidence that the treatment is working.
How is Victoria doing? Listen to find out!
Click below to hear the stories, or download wherever you get your podcasts:
A Revolutionary Experiment To Edit Human Genes
Short Wave | NPR | November 4, 2019
Gene-Edited ‘Supercells’ Make Progress In Fight Against Sickle Cell Disease
Morning Edition | NPR | November 19, 2019