In the early months of 2020, the global threat of COVID-19 united the scientific community. At the IGI, we created a pop-up coronavirus testing lab in our building on UC Berkeley campus over the course of three weeks. We tested patient samples from the UC Berkeley community, as well as first responders in the area, and vulnerable people without insurance or permanent housing. We developed new protocols for COVID testing, launched mobile testing for California farmworkers, and developed new rapid testing technology and clinical assays. Our scientists quickly formed rapid response research teams, working to better understand, detect, track, and treat the virus.
At the end of 2022, after processing over 650,000 tests, the IGI halted its COVID testing operations, but IGI investigators are still working on COVID-related research, and the IGI Clinical Laboratory is expanding its role in the institute as part of the Interventional Genomics Unit. Learn more and find resources below.
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(2022)Parker AM, Jackson N, Awasthi S, Kim H, Alwan T, Wyllie AL, Baldwin AB, Brennick NB, Moehle EA, Giannikopoulos P, Kogut K, Holland N, Mora-Wyrobek A, Eskenazi B, Riley LW, and Lewnard JA.Ā Clinical Infectious Diseases
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(2022)Syed AM, Ciling A, Taha TY...Ott M, and Doudna JA.Ā PNAS
(2022)Knyazev S, Chhugani K, Sarwal V, Ayyala R, Singh H, Karthikeyan S, Deshpande D, Baykal PI, Comarova Z, Lu A, Porozov Y, Vasylyeva TI, Wertheim JO, Tierney BT, Chiu CY, Sun R, Wu A, Abedalthagafi MS, Pak VM, Nagaraj SH, Smith AL, Skums P, Pasaniuc B, Komissarov A, Mason CE, Bortz E, Lemey P, Kondrashov F, Beerenwinkel N, Lam TT-Y, Wu NC, Zelikovsky A, Knight R, Crandall KA, and Mangul S. Nature Methods
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(2021)Stahl EC, Gopez AR, Tsuchida CA, Fan VB, Moehle EA, Witkowsky LB, Hamilton JR, Lin-Shiao E, McElroy M, McDevitt SL, Ciling A, Tsui CK, Pestal K, Gildea HK, Keller A, Sylvain IA, Williams C, Hirsh A, Ehrenberg AJ, Kantor R, Metzger M, Nelson KL, Urnov FD, Ringeisen BR, Giannikopoulos P, Doudna JA, and the IGI Testing Consortium. PLoS One
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(2021)Mora AM, Lewnard JA, Kogut K, Rauch SA, Hernandez S, Wong MP, Huen K, Chang C, Jewell NP, Holland N, Harris E, Cuevas M, Eskenazi B, and the CHAMACOS-Project-19 Study Team. JAMA Network
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(2021)Adams C, Horton M, Solomon O...Coloma J, Lewnard JA, Harris E, and Barcellos LF.Ā PLOS Global Public Health
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(2021)Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, DĆaz de LeĆ³n Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW,Ā Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ, IGI Testing Consortium, Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, and Doudna JA. Nature Chemical Biology
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(2021)Biering SB, Van Dis E, Wehri E...Ott M, Murthy N, Nomura DK, Schaletzky J and Stanley SA.Ā ACS Infectious Diseases
(2021)Jeong S, GonzĆ”lez-GrandĆo E, Navarro N, Pinals RL, Ledesma F, Yang D, and Landry MP.Ā ACS Nano
(2021)Ehrenberg AJ, Moehle EA, Brook CE, Cate AHD, Witkowsky LB, Sachdeva R, Hirsh A, Barry K, Hamilton JR, Lin-Shiao E, McDevitt S, Valentin-Alvarado L, Letourneau KN, Hunter L, Keller A, Pestal K, Frankino PA, Murley A, Nandakumar D, Stahl EC, Tsuchida CA, Gildea HK, Murdock AG, Hochstrasser ML, OāBrien E, Ciling A, Tsitsiklis A, Worden K, Dugast-Darzacq C, Hays SG, Barber CC, McGarrigle R, Lam EK, Ensminger DC, Bardet L, Sherry C, Harte A, Nicolette G, Giannikopoulos P, Hockemeyer D, Petersen M, Urnov FD, Ringeisen BR, Boots M, and Doudna JA on behalf of the IGI SARS-CoV-2 Testing Consortium. PLoS One
(2021)Deng X, Garcia-Knight MA, Khalid MM, Servellita V, Wang C, Morris MK, Sotomayor-GonzƔlez A, Glasner DR, Reyes KR, Gliwa AS, Reddy NP, San Martin CS, Federman S, Cheng J, Balcerek J, Taylor J, Streithorst JA, Miller S, Sreekumar B, Chen PY, Schulze-Gahmen U, Taha TY, Hayashi J, Simoneau CR, Kumar GR, McMahon S, Lidsky PV, Xiao Y, Hemarajata P, Green NM, Espinosa A, Kath C, Haw M, Bell J, Hacker JK, Hanson C, Wadford DA, Anaya C, Ferguson D, Frankino PA, Shivram H, Lareau LF, Wyman SK, Ott M, Andino R, and Chiu CY. Cell
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(2021)Crits-Christoph A, Kantor RS, Olm MR, Whitney ON, Al-Shayeb B, Lou YC, Flamholz A, Kennedy LC, Greenwald H, Hinkle A, Hetzel J, Spitzer S, Koble J, Tan A, Hyde F, Schroth G, Kuersten S, Banfield JF, and Nelson KL. American Society for Microbiology
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(2020)Featherstone JD, Barnett GA, Ruiz JB, Zhuang Y, and Millam BJ. ScienceDirect
(2020)Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas II DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk RP, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, and Marson A. Nature Biotechnology
(2020)Deng X, Gu W, Federman S, Plessis LD, Pybus OG, Faria NR, Wang C, Yu G, Bushnell B, Pan CY, Guevara H, Sotomayor-Gonzalez A, Zorn K, Gopez A, Servellita V, Hsu E, Miller S, Bedford T, Greninger AL, Roychoudhury P, Starita LM, Famulare M, Chu HY, Shendure J, Jerome KR, Anderson C, Gangavarapu K, Zeller M, Spencer E, Andersen KG, MacCannell D, Paden CR, Li Y, Zhang J, Tong S, Armstrong G, Morrow S, Willis M, Matyas BT, Mase S, Kasirye O, Park M, Masinde G, Chan C, Yu AT, Chai SJ, Villarino Elsa, Bonin B, Wadford DA, and Chiu CY. Science
(2020)Bouhaddou M, Memon D, Meyer B, White KM, Rezelj VV, Marrero MC, Polacco BJ, Melnyk JE, Ulferts S, Kaake RM, Batra J, Richards AL, Stevenson E, Gordon DE, Rojc A, Obernier K, Fabius JM, Soucheray M, Miorin L, Moreno E, Koh C, Tran QD, Hardy A, Robinot R, Vallet T, Nilsson-Payant BE, Hernandez-Armenta C, Dunham A, Weigang S, Knerr J, Modak M, Quintero D, Zhou Y, Dugourd A, Valdeolivas A, Patil T, Li Q, HĆ¼ttenhain R, Cakir M, Muralidharan M, Kim M, Jang G, Tutuncuoglu B, Hiatt J, Guo JZ, Xu J, Bouhaddou S, Mathy CJP, Gaulton A, Manners EJ, FĆ©lix E, Shi Y, Goff M, Lim JK, McBride T, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, De wit E, Leach AR, Kortemme T, Shoichet B, Ott M, Saez-Rodriguez J, tenOever BR, Mullins D, Fischer ER, Kochs G, Grosse R, GarcĆa-Sastre A, Vignuzzi M, Johnson JR, Shokat KM, Swaney DL, Beltrao P, and Krogan NJ. CellĀ
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(2020)Hamilton J. The CRISPR Journal
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