![Image of a blue single guide RNA](https://innovativegenomics.org/wp-content/uploads/2024/06/sgRNA-1.png)
Glossary
Single-guide RNA (sgRNA)
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A version of the naturally occurring two-piece guide RNA complex engineered into a single, continuous sequence. The simplified single-guide RNA is used to direct the Cas9 protein to bind and cleave a particular DNA sequence for genome editing.
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