Glossary
dCas9
« Back to Glossary Index
Catalytically inactive, or “dead,” Cas9. This mutated version of the Cas9 protein cannot cut, but still binds tightly to a particular DNA sequence specified by the guide RNA. Can be used to physically block the process of transcription, turning off a specific gene, or to shuttle other proteins to a particular site in the genome.
« Back to Glossary IndexYou may also be interested in
IGI Seminar Series: Empowering Teachers, Transforming Classrooms: Advancing K-12 STEM Education
IGI Seminar Series: Writing DNA with RNA: Genome Engineering by Target-Primed Reverse Transcription
IGI Seminar Series: Synthetic biology for people and planet health