IGI Makes Progress Toward Treating
Sickle Cell Disease with CRISPR-Cas9

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National Geographic Magazine - August 2016


Technology Rewrite Our DNA?

TED Radio Hour interviews Sam Sternberg

The Future of Genomics Research DNA Editing - Innovative Genomics Initiative (IGI)

IGI Institute Launch

November 2016


October 12, 2016 - Science Translational Medicine sicklecd750

IGI Makes Progress Toward Treating Sickle Cell Disease with CRISPR-Cas9

IGI researchers have taken a key step toward a cure for sickle cell disease (SCD), using CRISPR-Cas9 genome engineering technology to reverse the disease-causing...

September 30, 2016 - Nuffield Council on Bioethics screen-shot-2016-09-30-at-11-33-14-am

Nuffield Council on Bioethics reviews Genome Engineering

This new report from the Nuffield Council on Bioethics presents an overview of current applications and the associated ethical considerations arising...

September 26, 2016 - IGI Press Center screen-shot-2016-09-26-at-9-28-47-am

CRISPR-C2c2: New addition to CRISPR toolbox may be useful as a low-cost diagnostic

Researchers in collaboration with IGI Executive Director Jennifer Doudna have expanded the role of the newly discovered CRISPR protein C2c2 that targets...

September 23, 2016 - eLife screen-shot-2016-10-03-at-12-05-47-pm

Next generation guide RNAs for genome-wide CRISPR screens

IGI Co-Director Jonathan Weissman, Scientific Director Jacob Corn, Research Scientist Chong Park, and other colleagues have developed the next generation...

September 21, 2016 - IGI Press Center screen-shot-2016-09-21-at-3-52-33-pm

CZI Biohub Launches New Biomedical Research Partnership

A new Bay Area research initiative was launched this morning by Priscilla Chan and Mark Zuckerberg and their Chan Zuckerberg Initiative, which will invest...

News Archive



Solving the mystery of rare diseases with technology and crowdfunding

In this TEDx talk, Dr. Jimmy Lin introduces viewers to children and families living with rare genetic diseases, and describes how the Rare Genomics Institute...


CRISPR Cas9, Bring Me a Gene

This musical ode to CRISPR-Cas9 technology explains how genomic engineering works inside cells, helps us understand how this powerful technology is already ...


What are genes, and how does genome engineering work?

This new animated video describes how genome engineering enables scientists to change genetic sequences by adding, replacing or removing sections of ...


Introduction to DNA, Protein Synthesis and Genomic Engineering

The two videos featured in this post show how proteins are made in a cell, using information found in the DNA code, and then how DNA is engineered using CRISPR-Cas9...

Education Archive

Blog - Making the Cut

October 16, 2016 0 Comments

Sequence replacement to cure sickle cell disease

My lab recently published a paper, together with outstanding co-corresponding authors David Martin (CHORI) and Dana Carroll (University of Utah), in which...

September 12, 2016 1 Comment

Improved knockout with Cas9

Cas9 is usually pretty good at gene knockout. Except when it isn’t. Most people who have gotten their feet wet with gene editing have had an experience like...

Blog Archive