Professor Dipa Sashital of Iowa State University will present her work on how guide RNA sequence identity shapes CRISPR-Cas immune response. CRISPR guide RNAs are derived from spacers, which are viral sequences that have been incorporated into the CRISPR arrays of host genomes. Dr. Sashital will unravel how spacer sequences impact the downstream mechanisms of CRISPR-Cas immune systems.
The IGI seminar series features a diverse range of speakers focusing on a variety of topics related to the Institute’s research programs. Following all seminars, attendees are invited to stay for a free lunch and talk with the seminar speaker.
Not all spacers are equal:
How Guide RNA Sequence Identity Shapes CRISPR-Cas Immune Response
Dr. Dipa Sashital
Assistant Professor, Department of Biochemistry, Biophysics, & Molecular Biology
Iowa State University