Published in 2016
Cornerstones of CRISPR-Cas in drug discovery and therapy.
Fellmann C, Gowen BG, Lin PC, Doudna JA, and Corn JE. Nature Reviews Drug Discovery (2016).
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, and Weissman JS. Cell (2016).
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, and Weissman JS. eLife (2016).
Selection-free Genome Editing of the Sickle Mutation in Human Adult Hematopoietic Stem/Progenitor Cells. DeWitt MA, Magis W, Bray NL, Wang T, Berman JR, Urbinati F, Heo S, Mitros T, Muñoz DP, Boffelli D, Kohn DB, Walters MC, Carroll D, Martin DK, and Corn JE. Science Translational Medicine (2016). Pre-print (free to read)
Non-homologous DNA increases gene disruption efficiency by altering DNA repair outcomes. Richardson CD, Ray GJ, Bray NL, and Corn JE. Nature Communications (2016).